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Cholesterol builds in the arteries, valves and muscle of the heart Both Lipitor and Zocor belong to the class of drugs known as “statins”, which lower cholesterol by blocking the enzyme in the liver that produces bad cholesterol. Continue Shopping Clear Basket. Zocor is effective alone or when used concomitantly with bile-acid sequestrants. The brand-name drugs are much more expensive than their generics. Zocor should help with the cholesterol already there. Prescribed for High Cholesterol, Hyperlipoproteinemia, High Cholesterol - Familial more. In a recent study done by Phizer the producer of Lipitor, it was found that Lipitor was no better at preventing major heart complications than its leading competitor Zocor Lipitor is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. Used with Both Lipitor and Zocor should be combined with health, diet and exercise. 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